Expression of NKX 3.1 in Sertoli Cell Tumors
نویسندگان
چکیده
Objective: To evaluate the NKX3.1 expression by immunohistochemistry in normal testicular parenchyma and Sertoli cell tumours Leydig of testes ovary.
 Study Design: Retrospective longitudinal study.
 Place Duration Study: Shaukat Khanum Memorial Cancer Hospital Research Centre, Lahore Pakistan, from 2010-2021.
 Methodology: We used to positivity loss nuclear tumour (11 cases), (31 cases) (7 cases).
 Results: In our study, there were 49 cases. All cases benign expressed with staining NKX 3.1 cells. Two out 11 component (18.18%) 9 showed (81.8%). 3.1.
 Conclusion: Nuclear is seen cells parenchyma. This lost tumours.
منابع مشابه
Sertoli Cell Tumors in Dogs- a Report of Four Cases
Four male non descript dogs aged between 58 years were presented to the Department of Veterinary Surgery and Radiology, College of Veterinary Science, Tirupati with the history of large size swelling at the ventral abdomen adjacent to the body of penis. Two dogs were apparently healthy with normal temperature, pulse and respiratory rates. In two dogs, there were a complaint of loss of hair and ...
متن کاملComparative immunohistochemical characterization of canine seminomas and Sertoli cell tumors
Primary testicular tumors are the most common causes of cancer in male dogs. Overall, the majority of canine patients should be cured by testicular surgery. However, tumor markers are not well-known in veterinary medicine. We sought to determine using immunohistochemistry whether the combined human testicular tumor markers (placental alkaline phosphatase, OCT3/4, CD30, alpha-fetoprotein, inhibi...
متن کاملClinicopathologic features of ovarian Sertoli-Leydig cell tumors.
BACKGROUND Ovarian Stertoli-Ledig cell tumor (SLCT) is a rare type of sex cord-stromal tumor of the ovary. The present study was to evaluate clinicalopahologic features and prognosis of patients with Sertoli-Leydig cell tumor treated by surgery and adjuvant chemotherapy during short term follow-up. METHODS A total of sixteen patients with ovarian Sertoli-Leydig cell tumor treated at the Obste...
متن کاملExpression Status of UBE2Q2 in Colorectal Primary Tumors and Cell Lines
Background: Activation of the ubiquitin-proteasome pathway in various malignancies, including colorectal cancer, is established. This pathway mediates the degradation of damaged proteins and regulates growth and stress response. The novel human gene, UBE2Q2, with a putative ubiquitin-conjugating enzyme activity, is reported to be overexpressed in some malignancies. We sought to investigate the ...
متن کاملOvarian Sertoli–Leydig cell tumors: MRI findings and pathological correlation
BACKGROUND To investigate the magnetic resonance imaging (MRI) characteristics of ovarian Sertoli-Leydig cell tumors (SLCT). METHODS The clinical, MRI and pathological findings of five cases of SLCT were reviewed retrospectively. MRI appearances of tumors including laterality, shape and size, architecture, wall, septa and vegetation, signal intensity and contrast-enhancement pattern were eval...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pakistan Armed Forces Medical Journal
سال: 2022
ISSN: ['2411-8842', '0030-9648']
DOI: https://doi.org/10.51253/pafmj.v72i6.6430